Cart
sales@molnova.com
Homo-PROTAC cereblon degrader 1
CAS No. 2244520-98-5
Homo-PROTAC cereblon degrader 1( —— )
Catalog No. M21750 CAS No. 2244520-98-5
Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 93 | In Stock |
|
| 5MG | 163 | In Stock |
|
| 10MG | 282 | In Stock |
|
| 25MG | 432 | In Stock |
|
| 50MG | 677 | In Stock |
|
| 100MG | 1079 | In Stock |
|
| 200MG | 1451 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameHomo-PROTAC cereblon degrader 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionHomo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
-
DescriptionHomo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2244520-98-5
-
Formula Weight660.63
-
Molecular FormulaC??H??N?O??
-
Purity>98% (HPLC)
-
SolubilityDMSO : 200 mg/mL (302.74 mM; Need ultrasonic)
-
SMILESO=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCOCCOCCNC4=C5C(C(N(C6CCC(NC6=O)=O)C5=O)=O)=CC=C4)=C3C1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.
molnova catalog
related products
-
Azido-PEG1-azide
Azido-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
dBET57
dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=500 nM).
-
BCL6 PROTAC 15
BCL6 PROTAC 15 is a novel B-cell lymphoma 6 (BCL6) PROTAC, significantly degrade BCL6 in a number of DLBCL cell lines.
